肺泡微结石症(PAM)是一种少见的呼吸系疾病。Harbtz于1918年首先报告,国外报道约百余例,国内文献已报道36例,其中多有明显的家族性,我们亦发现一起两例(兄妹二人)家族性肺泡微结石症,报告如下: 病例摘要例1:患者男性,18岁,学生,病案号74611,无任何症状,1980年6月因参加高考体检透视时发现两肺有粟粒状阴影,经某医院摄X线胸片诊断“粟粒型肺结核”,用抗结核药物异菸肼,链霉素等治疗6个月无效,而于1980年12月5日来我院门 Alveolar microlithiasis (PAM) is a rare respiratory disease. Harbtz first reported in 1918, about a hundred cases reported abroad, the domestic literature has been reported in 36 cases, of which more obvious familial, we also found two cases (two siblings) of familial alveolar microlithiasis, the report is as follows: Case summary 1: male patient, 18 years old, student, medical record number 74611, without any symptoms, in 1980 June due to participate in the examination of the national examination found that both lungs have miliary shadows, a hospital by X-ray diagnosis of “miliary Tuberculosis ”, with anti-TB drugs isoniazid, streptomycin and other 6-month treatment of invalid, and in December 5, 1980 came to my courtyard