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自1973年3月1日到1980年9月20日,有5,580名妇女在丹麦东部四个医院内进行了羊膜穿刺。所有染色体分析在哥本哈根Rigshospitalet染色体实验室内进行。所有病人都是在超声指导下进行羊膜穿刺。有40名妇女(0.7%)胎儿染色体分析未能完成。这样被检妇女数为5,540名,其中包括75名妇女分娩双生子,其中51人进行了双生的染色体分析,因此总数为5,591个染色体分析。按常规将羊水细胞分量于两个塑料培
From March 1, 1973 to September 20, 1980, 5,580 women underwent amniocentesis at four hospitals in eastern Denmark. All chromosome analyzes were performed at the Rigshospitalet Chromosome Laboratory in Copenhagen. All patients underwent amniocentesis under the guidance of ultrasound. Forty women (0.7%) failed to complete the fetal chromosomal analysis. As a result, the number of women seized was 5,540, including 75 birth twins, of whom 51 were twins for chromosome analysis, giving a total of 5,591 chromosome analyzes. According to conventional amniotic fluid cell components in two plastic training