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原发性空蝶鞍综合征易与垂体肿瘤混淆,为避免繁芜的内分泌功能试验及创伤性检查,作者试图测定血清催乳激素(prolactin,PL)的昼夜节律变化以资与垂体肿瘤鉴别。本文报道37名正常对照者(正常男子组11例、绝经期前女子组18例、绝经期后女子组8例),7例原发性空蝶鞍综合征及16例不同病因的垂体肿瘤患者,测定血清 PL 的昼夜波动情况,包括24小时血清 PL的均值和 PL 的夜/昼比值。结果①正常对照组:24小时血清 PL 值在绝经期前女子组、绝经期后女子组和男子组分别为12.6±
Primary empty sella syndrome is easily confused with pituitary tumors. In order to avoid the endocrine function test and traumatic examination, the author attempts to determine the circadian rhythm of serum prolactin (PL) in order to identify the pituitary tumors. This article reports 37 normal controls (11 normal men, 18 premenopausal women and 8 postmenopausal women), 7 patients with primary empty sella syndrome and 16 patients with pituitary tumors of various etiologies Day-night fluctuations of serum PL were measured, including the mean of 24-hour serum PL and the night / day ratio of PL. Results ① In the control group, the serum level of PL in 24 hours before the menopause women group and the menopause group were 12.6 ±