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目的 :探讨肝素对人工晶体植入术后晶体表面色素沉着的影响及抑制后发障的效果 ,观察肝素对角膜水肿、眼压及眼内出血的影响。方法 :手术时为 76例的灌注液中加入 5 0U .ml- 1(0 .5mg .ml- 1)的肝素 ,其中老年性白内障 33例 ,糖尿病性白内障 2 4例 ,虹膜炎并发白内障 19例 (含外伤性白内障 5例 )。并随机选择普通人工晶体植入术 15 2例为对照 ,其中老年性白内障 98例 ,糖尿病性白内障 32例 ,陈旧性虹膜炎并发白内障 2 2例 (含外伤性白内障 9例 )。于术后 1、3、7d观察后囊混浊情况。结果 :应用肝素组术后人工晶体表面色素沉着明显较对照组轻 ,以 (+ )、( )、( )、( )分别代表微量、轻、中、重度色素沉着 ,对照组分别为 5 3.2 %、18.4 %、17.1%、11.3% ,肝素组则为 60 .4 %、17.2 %、15 .8%、8.5 %。后者 (+ )明显多于前者 ,而( )明显少于前者 ,两组差异有显著性 ,而 ( )、( )无明显差异。后发障对照组为 2 3.0 % ,糖尿病和虹膜炎性白内障为 33.3% ;肝素组为 15 .8% ,经肝素处理 ,糖尿病和虹膜炎性白内障为 2 3.3% ,两组差异有显著性 (P <0 .0 5和P <0 .0 0 1) ,角膜水肿程度 ,眼内压及眼内出血差异无显著性 (P >0 .0 5 )。结论 :肝素能明显抑制人工晶体植入术后晶体色素沉着及后发障 ,对角膜、眼压无影?
OBJECTIVE: To investigate the effect of heparin on crystal surface hyperplasia after intraocular lens implantation and the effect of inhibiting post-ocular obstruction. To observe the effect of heparin on corneal edema, intraocular pressure and intraocular hemorrhage. Methods: During the operation, 76 cases of heparin were added into the perfusion fluid of 50U.ml-1 (0.5mg. Ml-1), including 33 cases of senile cataract, 24 cases of diabetic cataract and 19 cases of iritis and cataract (Including traumatic cataract in 5 cases). Fifty-two cases of cataract were randomly selected. Fifty-two cases of senile cataract, thirty-two cases of diabetic cataract and twenty-two cases of cataract with old iritis (including 9 cases of traumatic cataract) were included in this study. The posterior capsular opacities were observed at 1, 3 and 7 days after operation. Results: The surface of intraocular lens in heparin group was significantly lighter than that in control group. The contents of (+), (), (), () were respectively trace, mild, moderate and severe hyperpigmentation. , 18.4%, 17.1% and 11.3% in the heparin group and 60.4%, 17.2%, 15.8% and 8.5% in the heparin group. The latter (+) was significantly more than the former, and () was significantly less than the former, the difference between the two groups was significant, and (), () no significant difference. In the control group with post-stroke, the incidence of cataract was 230% in diabetic control group and 33.3% in iritis group and 15.8% in heparin group. After heparin treatment, the incidence of diabetic and iris-induced cataract was 23.3% P <0.05 and P <0.01), corneal edema, intraocular pressure and intraocular hemorrhage no significant difference (P> 0.05). Conclusion: Heparin can significantly inhibit the post-implantation intraocular lens implantation and post-occipital disorders, the cornea, intraocular pressure without shadow?