本文报道二例患先天性重症肌无力同胞兄妹。例1:男性,7个月。四肢无力1月余,发热、咳嗽3天。足月顺产第一胎。母孕期患“感冒’。生后哭声响亮,四肢活动如常。父母体健,非近亲联姻。无特殊家族史。检查:声音嘶哑。无睑下垂。两肺呼吸音粗。双上肢肌力Ⅲ度,双下肢肌力Ⅱ度。实验室检查:白细胞10,100,中性37%,淋巴62%,嗜酸1%,红细胞375万,血红蛋白7.3克。父母及患儿染色体检 This article reports two cases of congenital myasthenia gravis and siblings. Example 1: Male, 7 months. Fever limbs more than 1 month, fever, cough for 3 days. Full-term first-born fetus. Pregnancy suffering from “cold.” After birth, loud crying, limb activity as usual .Parents healthy, non-cousins ​​marriage .No special family history .Check: hoarse voice. Degree, lower limb muscle strength Ⅱ degree. Laboratory tests: white blood cells 10,100, 37% neutral, lymphatic 62%, 1% acidophilus, erythrocytes 3.75 million, 7.3 grams of hemoglobin. Parents and children with chromosomal examination