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本实验以ＳＤ雄性大鼠为实验对象，采用碳粒血管内注射的方法，给动物造成一种全身性的非特异性免疫反应状态，以观察在这种状态下睾丸和垂体的激素分泌情况。动物经每天１次，共１０天的碳粒鼠尾静脉注射后，血浆睾酮的水平（０．８９６±０．３５８ｎｇ／ｄｌ，ｎ＝５）明显低于对照组（２．６５６±０．９９３ｎｇ／ｄｌ，ｎ＝７，Ｐ＜０．００５）；血浆ＬＨ（３．６７６±１．３５０ｍＩＵ／ｍｌ，ｎ＝９，４．６２７±２．５３９ｍＩＵ／ｍｌ，ｎ＝１０）两组比较无显著差异（Ｐ＞０．０５）；ＦＳＨ实验组（３．３６２±０．９２６ｍＩＵ／ｍｌ，ｎ＝９）与对照组相比明显降低（４．８９４±１．２３６ｍＩＵ／ｍｌ，ｎ＝１０，Ｐ＜０．０１）。实验组动物睾丸间质内ＡＣＰ阳性反应细胞增多，而β－羟基甾体脱氢酶反应消失。作者认为全身性的免疫反应既可以通过垂体也可以直接的作用于睾丸内的相关细胞，从而影响睾丸的功能。
In this experiment, SD male rats were used as experimental subjects and a systemic non-specific immune response was induced by intravascular carbon injection in order to observe the hormone secretion in testis and pituitary gland. The level of plasma testosterone (0.896 ± 0.358ng / dl, n = 5) was significantly lower than that of the control group (2.656 ± 0.993ng /dl,n=7,P<0.005); plasma LH (3.676 ± 1.350mIU / ml, n = 9,4.627 ± 2.539mIU / ml, n = 10) was no significant difference between the two groups (3.362 ± 0.926mIU / ml, n = 9) was significantly lower than that of the control group (4.894 ± 1.236mIU / ml, n = 10, P <0.01). In experimental group, ACP-positive cells in testicular interstitium increased, while β-hydroxy steroid dehydrogenase reaction disappeared. The author believes that the systemic immune response can not only through the pituitary also can directly affect the testicular cells, thus affecting the function of the testis.