患者女， ２３岁。因四肢僵硬１５年伴言语不清、右眼视物模糊入院。先出现左下肢跛行，渐累及右下肢，行走不稳，并波及双上肢，伴阵发性四肢抽搐，以情绪激动时明显，无意识丧失，四肢僵伴发作性抽搐表现为晨轻午重。近３年来，症状加重明显，右眼视力减退及言语不清，生活不 Female patient, 23 years old. Stiff limbs for 15 years with unclear speech, blurred vision right eye hospitalization. The first appeared lower limb limp, gradually lower extremities and legs, walking instability, and spread to both upper extremities, with paroxysmal convulsions of the limbs to emotionally significant when the loss of unconsciousness, limbs with episodes of seizures showed morning light afternoon weight. Over the past three years, the symptoms worsened, visual acuity and poor speech in the right eye, life is not