为了了解驻春胶囊对实验性骨质疏松大鼠的治疗作用 ,采用长期糖皮质激素造成肾虚而诱导的骨质疏松大鼠为模型 ,观察了驻春胶囊对大鼠椎骨和股骨的力学性能方面的影响。结果显示 ,用药 6 0天后 ,实验组大鼠股骨的最大载荷和变形位能及L4 椎骨的最大载荷和最大应力等力学参数与模型组比较有显著提高 (P <0 .0 5 )。表明驻春胶囊能提高皮质骨的抗冲击能力 ,改善松质骨的抗挤压能力 ,对实验性骨质疏松大鼠有积极的防治作用 In order to understand the therapeutic effect of Zhuchun Capsule on experimental osteoporosis in rats, a rat model of osteoporosis induced by chronic glucocorticoid-induced kidney deficiency was used as a model to observe the mechanical properties of rat vertebrae and femurs in Zhuchun Capsule. Impact. The results showed that after 60 days of treatment, the maximum load and deformation energy of the femur of the experimental group and the maximum load and maximum stress of the L4 vertebrae were significantly higher than those of the model group (P < 0.05). It is shown that gargle capsules can improve the impact resistance of cortical bone and improve the anti-extrusion ability of cancellous bone, and have a positive preventive effect on experimental osteoporosis rats.