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目的观察胰岛素治疗老年2型糖尿病的临床效果。方法将180例老年2型糖尿病随机分为观察组和对照组各90例。观察组应用皮下注射胰岛素治疗,对照组应用口服降糖药治疗。治疗后比较2组临床疗效及空腹血糖(FPG)、餐后2h血糖(2hPG)、糖化血红蛋白(HbA1c)变化情况。结果观察组总有效率为95.6%高于对照组的56.7%,差异有统计学意义(P<0.05)。2组治疗后FPG、2hPG、HbA1c均低于治疗前,且观察组改善情况优于对照组,差异均有统计学意义(P<0.05)。结论胰岛素治疗老年2型糖尿病效果显著,值得临床推广应用。
Objective To observe the clinical effect of insulin on type 2 diabetes in the elderly. Methods 180 cases of type 2 diabetes mellitus were randomly divided into observation group and control group of 90 cases. The observation group was subcutaneously injected with insulin, while the control group was treated with oral hypoglycemic agents. After treatment, the clinical efficacy, fasting blood glucose (FPG), 2h postprandial blood glucose (2hPG) and HbA1c were compared between the two groups. Results The total effective rate in the observation group was 95.6%, which was significantly higher than that in the control group (56.7%, P <0.05). The FPG, 2hPG and HbA1c in two groups were lower than those before treatment, and the improvement in the observation group was better than that in the control group (P <0.05). Conclusion Insulin treatment of type 2 diabetes in elderly patients with significant effect, it is worthy of clinical application.