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目的探讨胸腔镜胸腺扩大切除术治疗重症肌无力临床效果。方法选取2011年8月至2014年7月收治的重症肌无力患者64例,根据手术方法的不同随机分为研究组与对照组各32例,研究组患者予以胸腔镜胸腺扩大切除术治疗,对照组患者予以胸骨劈开胸腺切除治疗,观察对比两组治疗后效果、并发症情况以及手术时间、出血量、术后住院时间等。结果研究组和对照组治疗效果相当,手术时间相近,且并发症均较少,(P>0.05),差异无统计学意义;两组术中出血量、术后住院时间比较,研究组显著优于对照组(P<0.01),差异具有统计学意义。结论胸腔镜胸腺扩大切除术治疗重症肌无力效果显著,并发症少,创伤小,术中出血量少,安全性高,患者恢复快,值得临床推广应用。
Objective To investigate the clinical effect of thoracoscopic thymus enlargement resection for myasthenia gravis. Methods Sixty-four patients with myasthenia gravis treated in our hospital from August 2011 to July 2014 were randomly divided into study group (32 cases) and control group (32 cases) according to different surgical methods. Patients in study group were treated by thoracoscopic thymus enlargement resection. The patients were treated by sternotomy and thoracotomy. The effects and complications of the two groups were observed and compared, as well as the operation time, bleeding volume and postoperative hospital stay. Results The study group and the control group had similar treatment effect and similar operation time with fewer complications (P> 0.05), and the difference was not statistically significant. The bleeding volume and postoperative hospital stay in both groups were significantly better In the control group (P <0.01), the difference was statistically significant. Conclusions Thoracoscopic thymus enlargement resection is effective in treating myasthenia gravis with less complications, less trauma, less intraoperative bleeding, higher safety and faster recovery of patients. It is worthy of clinical application.