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用对流免疫电泳检查肿瘤病人,非肿瘤病人、足月新生儿和孕妇的血清甲胎蛋白(α-FP)。原发性肝癌(59%)和性腺畸胎瘤α-FP呈阳性,一例结肠癌肝转移病人以及100%的新生儿脐带血清也呈阳性反应。对流免疫电泳分析的灵敏度居于双扩散和放射免疫测定之间,所以这一方法可用于临床常规检查。本研究还测定了肝癌病人以及由健康的献血者和除肝癌以外
Serum alpha-fetoprotein (α-FP) levels in tumor patients, non-tumor patients, term newborns, and pregnant women were examined by convection immunoelectrophoresis. Primary liver cancer (59%) and gonad teratoma α-FP were positive. One case of colon cancer liver metastases and 100% of newborn umbilical cord serum were also positive. The sensitivity of the counter immunoelectrophoretic analysis lies between double diffusion and radioimmunoassay, so this method can be used for routine clinical examination. The study also measured liver cancer patients, as well as from healthy blood donors and other than liver cancer.