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目的探讨脑卒中类型、病程及病灶大小、部位对血清同型半胱氨酸(Hcy)水平的影响。方法检测359例急性脑卒中患者(脑梗死269例,脑出血90例)的血清Hcy水平,比较脑卒中不同类型、发病(首发与再发)、病程及病灶大小、部位患者之间的血清Hcy水平。结果脑梗死组与脑出血组、脑卒中首发组与再发组、不同病程及病灶大小、部位组之间的血清Hcy水平差异均无统计学意义(均P>0.05)。结论脑卒中类型、病程及病灶大小和部位对血清Hcy水平无明显影响。
Objective To investigate the effects of stroke type, course of disease, size of lesion and location on serum homocysteine (Hcy) level. Methods The serum levels of Hcy in 359 acute stroke patients (269 cerebral infarction and 90 cerebral hemorrhage) were determined. The serum Hcy levels were compared among different types of stroke patients (onset and recurrence), duration of disease and size of lesion. Level. Results There was no significant difference in serum Hcy levels between cerebral infarction group and cerebral hemorrhage group, stroke initial group and recurrence group, different course of disease, lesion size and site group (all P> 0.05). Conclusion Stroke type, course of disease, lesion size and location have no significant effect on serum Hcy level.