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目的探讨中晚期卵巢癌术后化疗的临床疗效分析。方法回顾性分析某院自2009年10月~2011年1月收治的36例中晚期卵巢癌进行化疗患者,将患者随机分为常规穿刺术20例,皮下植入化疗泵16例,观察两组的一次穿刺成功率、完成化疗疗程的情况及不良反应。结果常规组穿刺53次,一次成功率为83.0%,二次成功率为17.0%,化疗泵组总穿刺数42次,一次成功率为97.6%,二次成功率为2.4%。两组穿刺(P﹤0.05)。常规组完成疗程45%,化疗泵组完成疗程81.2%(P﹤0.05)。两组均出现不同程度的不良反应。结论皮下植入化疗泵与常规穿刺术组比较,植入化疗泵一次穿刺成功率、完成化疗疗程及不良反应方面具有显著优势。
Objective To investigate the clinical efficacy of postoperative chemotherapy for advanced ovarian cancer. Methods A retrospective analysis of a hospital from October 2009 to January 2011 admitted to the 36 cases of advanced ovarian cancer patients undergoing chemotherapy, the patients were randomly divided into routine puncture in 20 cases, subcutaneous implantation of chemotherapy pump in 16 cases, two groups were observed The success rate of a puncture to complete the course of chemotherapy and adverse reactions. Results 53 cases were punctured in the conventional group. The success rate was 83.0%, the secondary success rate was 17.0%. The total number of punctures in the chemotherapy pump group was 42. The success rate was 97.6% and the secondary success rate was 2.4%. Two groups puncture (P <0.05). The routine group completed 45% of the courses, while the chemotherapy group completed 81.2% of the courses (P <0.05). Both groups showed different degrees of adverse reactions. Conclusion Compared with the conventional puncture group, the successful rate of one-puncturation of the chemotherapy pump and the successful completion of the course of chemotherapy and adverse reactions are significant.