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目的了解我院急诊内科抗菌药物使用情况,指导临床合理用药。方法随机抽取我院2010年6月急诊内科2 389张处方。根据药品说明书及相关资料,对抗菌药物使用的品种、用药频度(DDDs)、药物利用指数(DUI)、联用情况进行分析。结果 2 389张处方中,含有抗菌药物的处方987张,抗菌药物使用率为41.31%。抗菌药物涉及7类27个品种,主要是头孢菌素类、大环内酯类和青霉素类等;以单用为主(占81.97%),其次为二联(占16.62%),三联少见(占1.41%)。DDDs排序前3位依次是阿奇霉素注射剂、依替米星注射剂和头孢唑肟钠注射剂。DDDs排名前10位的药物中4个头孢菌素类DUI值均>1。结论我院急诊内科抗菌药物的使用欠合理,抗菌药物合理使用仍需进一步提高。
Objective To understand the use of antimicrobial drugs in emergency department of our hospital to guide clinical rational drug use. Methods A total of 2 389 prescriptions in emergency department of our hospital in June 2010 were collected. According to the drug specification and related materials, the types of antimicrobial drugs used, frequency of drug use (DDDs), drug utilization index (DUI), combined with the analysis. Results Among the 2 389 prescriptions, 987 prescriptions containing antibacterials were used, and the antibacterial usage rate was 41.31%. Antibacterials involved 27 types of 27 varieties, mainly cephalosporins, macrolides and penicillins; single used mainly (accounting for 81.97%), followed by two (16.62%), triple rare Accounting for 1.41%). DDDs ranked first three followed by azithromycin injection, etimicin injection and ceftizoxime sodium injection. Four cephalosporin DUI values in the top 10 DDDs were> 1. Conclusion The use of antimicrobial agents in emergency department of our hospital is not reasonable and the rational use of antimicrobial agents still needs to be further improved.