近年来 ,由于细胞分子生物学技术的发展 ,有关细胞因子在肾脏疾病中介导免疫应答和炎症反应的研究日益广泛和深入。现已证实 ,几乎所有肾脏固有细胞均具有产生细胞因子的能力。这些细胞如果在抗原、有丝分裂原、细胞因子或其它激活剂的刺激下被活化 ,通过自分泌 (ａｕｔｏｃｒ In recent years, due to the development of cell molecular biology techniques, the research on cytokines mediated immune response and inflammatory response in kidney disease is more and more extensive and in-depth. It has been demonstrated that almost all innate kidney cells have the ability to produce cytokines. These cells, if stimulated by antigens, mitogens, cytokines or other activators, are activated by autocr