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采用粒一单祖细胞(CFU-GM)体外培养技术,观察28例Ⅱ型登革病毒(D_2V)对CFU-GM集落生长的影响。与对照组比较。显示D_2V感染组CFU-GM集落产率明显减少(P<0.01),从而证实在体外D_2V能抑制CFU-GM增殖,提示登革出血热病人病初粒细胞减少与CFU-GM受D_2V抑制有关。
The effects of 28 dengue virus type Ⅱ (D_2V) on the CFU-GM colonies growth were observed by CFU-GM in vitro culture. Compared with the control group. The results showed that D_2V could inhibit the proliferation of CFU-GM in vitro, suggesting that the reduction of CFU-GM in D_2V infection group was related to the inhibition of D_2V by CFU-GM.