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作者报导了83例儿童和成人急性髓性白血病(简称AML)的治疗结果,其中粒细胞型48例,粒-单核细胞型19例,单核细胞型7例,早幼粒细胞型9例。年龄为4个月至49岁。58例(70%)获得完全缓解,其中40例仅用了一个诱导疗程,18例用了两个诱导疗程。诱导方案如下: 在第一个疗程开始后14天,做骨髓穿刺和活检。结果骨髓增生低下(原始细胞<5%),则第二个疗程推迟到复查髓象原始细胞再度增生或完全缓解。如果在第14天骨髓原始细胞>5%和有核细胞占25%,则开始第二个诱导疗程。两个诱导疗程后,仍未完全缓解为无效。
The authors report the results of 83 children and adults with acute myelogenous leukemia (AML), of which 48 were granulocyte, 19 were monocyte-mononuclear, 7 were monocytic and 9 were promyelocytic . The age is from 4 months to 49 years old. Fifty-eight patients (70%) achieved complete remission, of which 40 used only one induction course and 18 used two induction courses. The induction schedule was as follows: Bone marrow aspirate and biopsy were performed 14 days after the first course of treatment. The results of low bone marrow hyperplasia (primitive cells <5%), then the second course of treatment was delayed to review the medullary primary cell proliferation or complete remission. If bone marrow blasts> 5% and nucleated cells account for 25% on day 14, then a second induction course is started. After two induction courses, still not completely relieved to be invalid.