目的了解蕉城区手足口病流行病学特征,为制订防控策略提供依据。方法用描述性流行病学方法对蕉城区2009—2012年手足口病疫情数据进行分析。结果 2009—2012年蕉城区手足口病发病5 468例,重症71例,年均发病率318.32/10万,重症率12.98‰;疫情呈散发态势,城区和城乡结合部发病率较高;聚集性疫情20起99例,均发生在托幼机构;发病双高峰为5~6月和10~11月;发病率男女性别比为1.3∶1,以散居儿童和幼托儿童为主(94.4%),高发人群为0~3岁组(84.9%);重症病例中0~3岁占94.4%,年龄越小重症率越高趋势;由EV71、CoxA16和其他肠道病毒混合感染,EV71占85.0%。结论手足口病有明显季节性和性别、年龄、职业差异,应加强重点机构及重点人群的防控措施。 Objective To understand the epidemiological characteristics of hand-foot-mouth disease in Jiaocheng district and provide the basis for the development of prevention and control strategies. Methods Descriptive epidemiological methods were used to analyze the epidemic data of hand-foot-mouth disease in Jiaocheng district from 2009 to 2012. Results In 2009-2012, 5 468 HFMD cases were found in Jiaocheng District, 71 cases were severe and the average annual incidence was 318.32 / 100 000 and the critical rate was 12.98 ‰. The epidemic situation was exuberant and the incidence rate was higher in urban and rural areas. The epidemic outbreak occurred in 99 cases in both nurseries and kindergartens. The double peak incidence was from May to June and from October to November. The incidence of male to female ratio was 1.3: 1, mainly in scattered children and preschool children (94.4%). (84.9%) in the high-risk population, 94.4% (0-3 years) in the severe cases, and the younger the age were. The EV71, CoxA16 and other enterovirus infections were more common, with EV71 accounting for 85.0% . Conclusion Hand, foot and mouth disease is obviously seasonal and gender, age, occupational differences, prevention and control measures should be strengthened in key institutions and key populations.