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目的:探讨我院尿路感染的病原菌分布以及耐药性监测,为临床经验治疗提供依据。方法:回顾性分析2015年1月—2016年12月,疑似泌尿系统感染的患者,留取清洁中段尿进行培养及药敏试验。结果:2年医院尿路感染的病例共分离出549株病原菌。以大肠埃希菌为主,共检出296株,占分离率的53.9%。其次是屎肠球菌、肺炎克雷伯菌分别检出65株和41株,分别占11.8%、7.5%。真菌分离出50株,占分离率的9.1%。大肠埃希菌对碳青霉烯类抗菌药物高度敏感,对哌拉西林/他唑巴坦、头孢吡肟、阿米卡星,亦具有良好的抗菌活性。肠球菌对万古霉素高度敏感。结论:大肠埃希菌任是我院泌尿系统感染患者最常见的病原菌,且耐药性较为严重,应该加强病原菌培养及药物敏感试验,对临床合理应用抗菌药物具有重要意义。
Objective: To investigate the distribution of pathogenic bacteria in urinary tract infection in our hospital and the monitoring of drug resistance, so as to provide basis for clinical experience and treatment. Methods: From January 2015 to December 2016, patients with suspected urinary tract infection were retrospectively analyzed. Urine samples were collected for culture and susceptibility testing. Results: A total of 549 strains of pathogens were isolated from urinary tract infections in hospital in 2 years. Escherichia coli-based, a total of 296 strains were detected, accounting for 53.9% of the isolation rate. Followed by Enterococcus faecium, Klebsiella pneumoniae were detected in 65 and 41 strains, accounting for 11.8%, 7.5%. Fifty fungi isolated, accounting for 9.1% of the isolation rate. Escherichia coli is highly sensitive to carbapenem-based antibiotics and has good antibacterial activity against piperacillin / tazobactam, cefepime and amikacin. Enterococci are highly susceptible to vancomycin. Conclusion: Escherichia coli is the most common pathogen of urinary tract infection in our hospital, and the drug resistance is more serious. Pathogen culture and drug susceptibility testing should be strengthened, which is of great significance to the clinical application of antibacterial drugs.