巨球蛋白血症国内仅见个例文献,现将我院近年所见3例报告如下。例1,男,45岁。1985年5月感面黄,乏力,低热而入院。既往体健。查体:中度贫血貌,浅淋巴结不大,心肺(一),肝肋下3cm,脾肋下6cm,质中无压痛。实验室检查:入院时Hb41g/L、WBC5.0×10~9/L、N 55%、L43%、E2%、BPC50×10~9/L,髓象有核细胞增生明显活跃,粒系、红系增生减低,淋巴细胞系增生活跃,成淋48.4%,幼淋29.2%,POX原幼细胞(-),拟诊急淋。用联合化疗柔红霉素+长春新碱+强的松方案,病情恶化。入院5月后查血IgM高达5200mg%,尿蛋 Only a case of macroglobulinemia literature, now in our hospital seen in 3 cases reported in recent years are as follows. Example 1, male, 45 years old. May 1985 face yellow, fatigue, fever and admission. Past physical health. Physical examination: moderate anemia appearance, small lymph nodes, heart and lung (a), liver ribs 3cm, spleen ribs 6cm, no tenderness in the quality. Laboratory examination: admission of Hb41g / L, WBC5.0 × 10 ~ 9 / L, N 55%, L43%, E2%, BPC50 × 10 ~ 9 / L, medullary nucleus significantly hyperplasia, Erythroid hyperplasia, lymphocytic hyperplasia active, into the drench 48.4%, 29.2% of young children, POX primary cells (-), the proposed emergency. With combination chemotherapy daunorubicin + vincristine + prednisone program, the condition worsened. After admission to check blood IgM up to 5200mg%, urine egg