病例摘要患者男性,44岁,已婚。病案号361962。因面容粗陋,肢端肥大8年,多饮多尿5年于1984年10月10日第三次住北京部队总医院。患者于1976年开始逐渐出现手足肥大,指(趾)增粗,头颅增大,同时面容改变,表现鼻大、唇厚,眉弓、颧骨突出。有持续头部胀痛,以额顶部为主,无恶心、呕吐,无视力、视野改变。多汗、思睡,性功能减退至阳萎。1979年出现多食、多饮、多尿,当时X线检查示蝶鞍扩大,空腹血糖470～900mg％,尿糖++++,尿酮体阴性。按糖尿病给以D_(860)和降糖灵治疗,临床“三多”症状一度改善血糖降至正常,尿糖转阴。1980年2 Case summary Patient Male, 44 years old, married. Case No. 361962. Due to rough face, acromegaly for 8 years, more than 5 years of drinking and polyuria on October 10, 1984 the third time living in Beijing General Hospital. In 1976, the patient began to gradually develop hand-foot hypertrophy, thickening of the fingers (toe), head enlargement, and changes in facial appearance, showing a large nose, thick lips, protruding eyebrows and cheekbones. Sustained head pain, mainly at the top of the forehead, no nausea, vomiting, no vision, visual field changes. Hyperhidrosis, sleepiness, sexual decline to impotence. In 1979, there was more food, more drink, and more urine. At that time, X-ray examination showed that the sella expanded, fasting blood glucose was 470-900 mg%, urine sugar ++++, and urine ketone body was negative. According to diabetes treatment with D_(860) and Jiangtangling, clinical “three more” symptoms once improved blood glucose to normal, and urine sugar turned negative. 1980 2