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目的探讨血清在血行转移的作用及机制。方法利用层粘连蛋白糖肽影响血清诱导的小鼠Ｂ１６黑色素瘤细胞凝集及其实验性转移。结果糖肽抑制血清诱导的Ｂ１６细胞凝集及其实验性肺转移。结论血清可能通过介导肿瘤细胞凝集，参与血行转移。
Objective To investigate the role and mechanism of serum transfer in blood. METHODS: Laminin glycopeptides were used to influence serum-induced agglutination of B16 melanoma cells and their experimental metastasis. Results Glycopeptides inhibited serum-induced B16 cell agglutination and its experimental lung metastasis. Conclusion Serum may participate in hematogenous metastasis by mediating tumor cell agglutination.