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目的:调研我院小儿社区获得性肺炎(CAP)住院患者抗菌药合理使用情况。方法:采用回顾性的调查方法,抽取我院2007年7月～2008年6月的1 167例小儿CAP患者病历,按年龄、性别、咽拭子涂片、痰培养结果,药敏试验、使用药物、联合用药、疗效等对资料进行统计分析。结果:1 167例小儿CAP患者,检出肺炎链球菌108例,大肠埃希菌36例,金黄色葡萄球菌27例,肺炎克雷伯菌20例,卡他莫拉菌18例。患者100%使用抗菌药,其中,联合使用抗菌药682例(58.4%);单独使用485例(41.6%)。结论:我院小儿CAP住院患者,抗菌药临床使用趋于合理,联合用药方法比单用方法治疗效果好,但存在不合理用药现象。
Objective: To investigate the rational use of antibacterials in hospitalized children with community-acquired pneumonia (CAP) in our hospital. Methods: A retrospective survey method was used to collect medical records of 1 167 children with CAP from July 2007 to June 2008 in our hospital. According to the age, gender, throat swab smear, sputum culture results and drug sensitivity test, Drugs, combination therapy, efficacy and other statistical analysis of the data. Results: A total of 1 167 cases of CAP in children were diagnosed as Streptococcus pneumoniae (108 cases), Escherichia coli (36 cases), Staphylococcus aureus (27 cases), Klebsiella pneumoniae (20 cases) and Moraxella catarrhalis (18 cases). Antibiotics were used in 100% of the patients, of which 682 were antibiotics (58.4%) and 485 (41.6%) were used alone. Conclusion: The clinical use of antibacterials in CAP pediatric patients in our hospital tends to be reasonable. The combination therapy is more effective than single treatment, but there is an irrational drug use.