炎症性肠病发病率逐年增加,病因复杂,病程长,难治愈易复发。胃肠道Cajal间质细胞及肥大细胞在炎症性肠病时均发生不同程度的异常改变,它们的分布、结构和数量异常,均与炎症性肠病的发病有关。本文就Cajal间质细胞和肥大细胞在炎症性肠病中的作用及相互关系作一综述。 The incidence of inflammatory bowel disease increased year by year, the etiology is complex, long duration, refractory and easy to relapse. Gastrointestinal Cajal interstitial cells and mast cells in inflammatory bowel disease occurred in varying degrees of abnormal changes in their distribution, structure and quantity, are associated with the incidence of inflammatory bowel disease. This review summarizes the roles and relationships of Cajal interstitial cells and mast cells in inflammatory bowel disease.