论文部分内容阅读
手足口病是由多种肠道病毒感染导致的一种急性儿科传染病。近年来,我国肠道病毒71型(EV71)手足口病发病率急剧上升,重症病例时有报道,严重威胁儿童健康。临床上对于重症手足口病的治疗缺乏有效手段,主要以对症治疗和支持疗法为主。静脉注射人免疫球蛋白由健康献血员血浆提取纯化而来,含有包括EV71在内的多种肠道病毒的中和抗体,可作为重症手足口病被动免疫和免疫调节的重要手段,值得关注。
Hand, foot and mouth disease is an acute pediatric infectious disease caused by a variety of enterovirus infections. In recent years, the incidence of hand-foot-mouth disease of enterovirus 71 (EV71) in our country has risen sharply, while cases of severe cases have been reported, which seriously threaten the health of children. Clinical treatment of severe HFMD lack of effective means, mainly symptomatic treatment and supportive therapy. Intravenous injection of human immunoglobulin from healthy blood donors extracted from the plasma purification, including a variety of enterovirus including EV71, including neutralizing antibodies, can be used as severe HFMD passive immunization and immunomodulatory means important, worth attention.