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目的是探讨乳化碘油增强CT对早期肝癌的诊断作用。方法采用乳化碘油：由碘化油、卵磷脂、甘油等经超声乳化而成：用二乙基亚硝胺诱导法建立大鼠肝癌模型（n＝4）：观察静脉注射乳化碘油（0.4ml／只）后，正常大鼠（n＝4），及大鼠肝癌病灶的强化情况，并与病理学检查进行对照分析。结果得到：乳化碘油能引起肝脾组织特异性显著强化：透视电镜证实肝细胞参与碘油乳粒的摄取：选取的4只大鼠肝癌模型中，共有14个瘤结，大小4、5±3.4mm；乳化碘油增强CT检出率85.7％（12／14）的瘤结，明显高于平扫时，病灶显示率（14．3％）。结论为乳化碘油是一种潜在的肝脾特异性造影剂，对早期肝癌的检出具有重要价值。
The purpose is to investigate the role of emulsified lipiodol in the diagnosis of early stage liver cancer by enhanced CT. Methods Lipiodol was emulsified by lipiodol, lecithin and glycerol. The model of hepatocellular carcinoma was established by diethylnitrosamine induction (n = 4). The effects of intravenous emulsification of lipiodol (0.4 ml / only), the normal rats (n = 4) and the enhancement of liver cancer lesions in rats, and compared with the pathological examination. The results showed that emulsified lipiodol could significantly enhance the tissue specificity of liver and spleen: the electron microscopy confirmed the involvement of hepatocytes in the uptake of lipiodol granule: In the four rat liver cancer models selected, there were 14 tumor nodes with the size of 4,5 ± 3.4mm; emulsified iodized oil enhanced CT detection rate of 85.7% (12/14) of the tumor knot was significantly higher than the plain scan, the lesion showed rate (14.3%). The conclusion is that emulsified lipiodol is a potential liver-spleen-specific contrast agent, which is of great value for the detection of early liver cancer.