ras 突变基因与某些哺乳动物细胞的转化有非常密切的关系,细胞转化后可形成肿瘤。因此,从某些恶性肿瘤细胞的ras 基因中可以测出点突变,这些突变基因能完成NIH3T3成纤维细胞的转化。然而,正常或突变ras 基因产生的P21蛋白(对应于其分子量)的生化功能仍未完全阐明。酵母菌saccharomyces The ras mutant gene has a very close relationship with the transformation of certain mammalian cells, which can form tumors after cell transformation. Therefore, point mutations can be detected from the ras gene in some malignant tumor cells. These mutant genes can complete the transformation of NIH3T3 fibroblasts. However, the biochemical function of the P21 protein (corresponding to its molecular weight) produced by the normal or mutant ras gene has not yet been fully elucidated. Yeast saccharomyces