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缺血性卒中患者发病头几小时内的病情变化很重要,这时可能是取得有效治疗的“最佳治疗时间(therapeutic window)”。目前,有关这方面的报道甚少。本文作者对1988年1月至1990年12月172例(男79,女93,年龄21～95岁,平均73.4±11.6岁)发病后6h内入院的缺血性卒中(除外腔隙性卒中及TIA)患者的病理生理、临床等指标进行评估,试图找出可预测卒中患者恢复情况的指标。 用修正的Rankin量表对172例患者卒中发病后30天和6个月的功能状态进行评分,对患者的性别、年龄、入院当天和第7天病情(如清醒程度、症状出现时间)、吸烟、高血压、糖尿病、心肌梗塞、心房纤
Changes in condition within the first few hours of onset of ischemic stroke are important and may be the “therapeutic window” for effective treatment. At present, little is reported in this area. The authors of this study randomized 172 patients (male 79, female 93, age 21-95 years, mean age 73.4 ± 11.6 years) admitted to hospital within 6 hours from January 1988 to December 1990 with ischemic stroke (excluding lacunar strokes and TIA) patients with pathophysiology, clinical and other indicators to assess, trying to find out the prognosis of patients with stroke recovery indicators. 172 patients were scored for functional status at 30 days and 6 months after onset of stroke using a modified Rankin scale. Patients’ sex, age, day of admission, and day 7 (such as degree of alertness, symptom onset), smoking Hypertension, Diabetes, Myocardial Infarction, Atrial Fibrillation