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目的探讨红细胞分布宽度(RDWC)对冠心病患者预后的影响。方法选择汤阴县人民医院心内科2007年6月-2011年3月确诊为冠心病患者1042例,死亡者44例(A组),存活者998例(B组),同期选择在本院健康体检的年龄相当正常人1384例作为正常对照组(C组),检测RDWC。结果 A组、B组、C组RDWC分别为14.59±1.99、12.98±0.99、12.43±0.72,A组与B组比较RDWC有显著差异(P=0.001);A组、B组与C组比较RDWC有显著差异(P<0.001);A组、B组、C组男女性别间无显著差异(P>0.05);RDWC增高组冠心病死亡率与RDWC正常组比较显著升高,有统计学差异(P<0.001)。结论冠心病组RDWC增大,RDWC增高组冠心病患者死亡率比RDWC正常组显著升高,因此,RDWC对冠心病患者的预后有影响,RDWC有望成为冠心病患者预后不良的危险因子。
Objective To investigate the influence of RDWC on the prognosis of patients with coronary heart disease. Methods From January 2007 to March 2011, 1042 patients with coronary heart disease were diagnosed in Tongyin People’s Hospital of Cardiology. 44 patients died (group A) and 998 survived (group B) A total of 1384 normal-aged people were selected as the normal control group (group C). RDWC was detected. Results The RDWC of group A, group B and group C were 14.59 ± 1.99, 12.98 ± 0.99 and 12.43 ± 0.72, respectively. There was significant difference of RDWC between group A and group B (P = 0.001) (P <0.001). There was no significant difference between male and female in group A, group B and group C (P> 0.05). The mortality of coronary heart disease in RDWC increased group was significantly higher than that in normal RDWC group P <0.001). Conclusion The RDWC in coronary heart disease group is increased. The mortality of coronary heart disease patients with elevated RDWC is significantly higher than that in normal RDWC group. Therefore, RDWC has an impact on the prognosis of patients with coronary heart disease. RDWC is expected to be a risk factor for poor prognosis in patients with coronary heart disease.