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美国著名的Barold教授于2012年4月在Europace杂志发表《一度房室阻滞与起搏治疗》的综述,阐述了一度房室阻滞病理生理认识的新观点。正常PR间期为120~200ms,≥300ms时为重度一度房室阻滞,≥350ms时称为PR间期过度延长。Framingham的资料表明:一度房室阻滞(PR>200ms)患者的全因死亡率增加,发生房颤的风险是正常人的2倍,置入起搏器的风险是正常人的3倍,一度房室阻滞常与器质性心脏病相关。而PR间期≥300ms的重度一度房室阻滞还可引起:①PR间期延长:多
The famous American Professor Barold published a review of “once atrioventricular block and pacing therapy” in the Europace magazine in April 2012, and elaborated the new viewpoints on the once-known pathophysiology of atrioventricular block. The normal PR interval of 120 ~ 200ms, ≥ 300ms when a severe degree of atrioventricular block, ≥ 350ms when the PR interval is called excessive extension. According to Framingham’s data, all-cause mortality in patients with atrioventricular block (PR> 200 ms) increased twice as often as that of a normal person and three times as much as that of a normal person Atrioventricular block often associated with organic heart disease. The PR interval ≥ 300ms atrioventricular block may also cause: ① prolongation of the PR: more