52例口服降糖药血糖控制不良的T2DM患者随机分为地特组26例,预混30R组26例,地特组三餐前服阿卡波糖,30R组中餐前加服阿卡波糖,根据血糖水平调整胰岛素用量,观察8周。结果:两组治疗后血糖及HbA1c较治疗前明显下降,C肽分泌改善,地特组空腹血糖下降更明显,空腹达标时间缩短,低血糖发生率低,并且体重无明显改变。 Twenty-two T2DM patients with poorly controlled blood glucose control were randomly assigned to 26 patients in the Detec group, 26 patients in the Premix 30R group, Acarbose before meals in the Dete group and Acarbose , Adjust the amount of insulin according to blood glucose levels, observed for 8 weeks. Results: After treatment, blood glucose and HbA1c were significantly decreased, C peptide secretion was improved, the fasting blood glucose of Depeche group was decreased more obviously, the fasting time was shortened, the incidence of hypoglycemia was lower, and body weight did not change significantly.