毛霉菌病是一种严重的致命性感染,诊断困难,死亡率高,已受到重视。一、发病率:有人统计国外2454例深部霉菌感染尸检报告毛霉菌病占3.5%,国内309例中毛霉菌病占2.3%。1977年Murray H.W回顾100年来有70例肺毛霉菌病报道,国内迄今约有10例报道。二、病因、基础疾病和诱因:毛霉菌病病因是毛霉菌感染,该霉菌广泛分布于自然界中,如土壤、肥料、水果等,亦常寄生于人体中,在人的口腔、鼻道、粪便中亦能获得,是一种条件致病菌,一旦机体抵抗力极度下降时可引起疾病。毛霉菌有特征性菌丝,菌丝形态祖大,粗细不均,宽约5～60μm,一般在10～15μm之间,菌丝分支不分节,分支呈直角或锐角,其终末之孢子囊柄可生出球状胞子 Mucormycosis is a serious, fatal infection that has been diagnosed and has high mortality rates. First, the incidence: Some statistics of 2454 foreign cases of deep mold infection autopsy report Mucormycosis accounted for 3.5%, 309 cases of domestic Mucormycosis accounted for 2.3%. Murray H.W in 1977 reviewed 70 cases of pulmonary mucormycosis reported in 100 years, so far about 10 cases reported. Second, the etiology, underlying diseases and incentives: the etiology of Mucormycosis is Mucormica infection, the mold is widely distributed in nature, such as soil, fertilizers, fruits, also often parasitic in the human body, in the human oral cavity, nasal passages, Can also be obtained, is a condition of pathogenic bacteria, once the body’s resistance to extreme decline can cause disease. Mucormomycetes have characteristic mycelium, mycelium morphological large, uneven thickness, width of 5 ~ 60μm, generally between 10 ~ 15μm, mycelial branch regardless of section, the branch was at right angles or acute angle, the terminal spores Pouch handle can produce spherical spores