论文部分内容阅读
目的研究孕妇阴道B族溶血性链球菌(GBS)的带菌率并研讨其对母婴预后的影响。方法 990例定期产检的孕妇,均在孕35~37周后采取孕妇阴道下段分泌物,进行细菌培养,分析GBS的携带率。将携带GBS的患者记为观察组,抽取同一时期不携带GBS的120例孕妇记为对照组,比较两组母婴结局。结果本文抽取的990例孕妇中有114例孕妇携带GBS细菌,带病率为11.5%。观察组孕妇流产的发生率为7.4%,早产为17.2%,胎膜早破为38.6%,均明显高于对照组孕妇的0.8%、2.5%及8.3%,差异均有统计学意义(P<0.05)。观察组孕妇胎儿窘迫的发生率为7.4%,虽低于对照组的8.3%,但差异无统计学意义(P>0.05)。观察组新生儿肺炎的发生率为5.9%,上呼吸道感染为30.9%,均明显高于对照组孕妇的0.8%及11.7%,差异均有统计学意义(P<0.05)。观察组新生儿窒息的发生率为4.4%,对照组为0.8%,组间比较差异无统计学意义(P>0.05)。结论本地区孕妇阴道GBS带菌率约为11.5%,GBS感染对母婴结局可造成严重后果,故需加强产前保健及GBS感染的筛查。
Objective To study the carrier rate of vaginal B serogroup B (GBS) in pregnant women and to study its influence on the prognosis of maternal and infant. Methods Nine hundred and ninety pregnant women who took regular check-ups were taken vaginal secretions of pregnant women 35-37 weeks after their pregnancy to carry out bacterial culture. The carrying rate of GBS was analyzed. The patients with GBS were recorded as observation group. 120 pregnant women who did not carry GBS during the same period were selected as the control group, and maternal and infant outcomes were compared between the two groups. Results Of the 990 pregnant women in this study, 114 pregnant women carried GBS bacteria with a prevalence of 11.5%. The incidence of miscarriage in observation group was 7.4%, premature birth was 17.2%, premature rupture of membranes was 38.6%, which were significantly higher than those in control group (0.8%, 2.5% and 8.3%, respectively), the differences were statistically significant (P < 0.05). The incidence of fetal distress in the observation group was 7.4%, which was lower than that in the control group (8.3%), but the difference was not statistically significant (P> 0.05). The incidence of neonatal pneumonia was 5.9% in the observation group and 30.9% in the upper respiratory tract infection group, which were significantly higher than those in the control group (0.8% and 11.7%, respectively). The differences were statistically significant (P <0.05). The incidence of neonatal asphyxia was 4.4% in the observation group and 0.8% in the control group, with no significant difference between the two groups (P> 0.05). Conclusion The prevalence rate of vaginal GBS in pregnant women in this area is about 11.5%. GBS infection can have serious consequences on maternal and infant outcomes. Therefore, prenatal care and GBS screening should be strengthened.