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对维生素A和它的类似物[类视黄质(retinoids)]予防化学诱发肿瘤的能力,已在不同的实验中加以研究。本文作者报告了另一种维生素A的类似物Ro-11-1430(N-乙基视黄质酰胺的三甲基甲氧基苯代化合物)可以显著地抑制辐射诱发的瘤性转化;该化合物的合成和结构,Bollag已作了描述。本实验的材料系采用传代13代和15代的C_3H
The ability of vitamin A and its analogues [retinoids] to prevent chemical induction of tumours has been studied in different experiments. The authors report that another analogue of vitamin A, Ro-11-1430 (trimethylmethoxybenzoyl N-ethylretinamide) can significantly inhibit radiation-induced neoplastic transformation; this compound The synthesis and structure of Bollag have been described. The material of this experiment was C_3H with 13 generations and 15 generations.