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目的探讨胃炎和胃溃疡患者治疗中的不合理用药情况。方法选取2014年1—12月长春市双阳区医院收治的胃炎和胃溃疡患者资料100例,均为采用受体阻滞剂联合抗酸药物等对患者进行治疗,分析其不合理用药情况,比较不合理用药与合理用药组患者的临床疗效、复发率及疗程。结果 100例胃炎、胃溃疡患者中,用药不合理39例,发生率为39.0%(39/100);其中药物配伍不当26例,剂量不合理3例,重复用药4例,药物选择不当5例,无指征用药1例;合理用药组患者的痊愈率明显高于不合理用药组,复发率明显低于不合理用药组,疗程明显短于不合理用药组,差异均有统计学意义(均P<0.05)。结论在对胃炎和胃溃疡患者的治疗中,不合理用药会造成患者出现各种不良反应,不仅影响患者的治愈率,还会延长患者的治疗时间并增加病情复发率。
Objective To investigate the irrational use of drugs in the treatment of patients with gastritis and gastric ulcer. Methods A total of 100 patients with gastritis and gastric ulcer admitted to Shuangyang District Hospital of Changchun City from January to December 2014 were selected. All patients were treated with receptor blockers and antacids, and their irrational drug use was analyzed. Irrational medication and rational use of drugs in patients with clinical efficacy, recurrence rate and course of treatment. Results Among the 100 patients with gastritis and gastric ulcer, 39 cases were irrational and the incidence rate was 39.0% (39/100). Among them, 26 cases were incompatible with drugs, 3 cases were irrational, 4 cases were repeated medication and 5 cases were improper medication selection , No indications for medication in 1 case; reasonable medication group patients cured rate was significantly higher than unreasonable drug group, the recurrence rate was significantly lower than unreasonable drug treatment group, treatment was significantly shorter than unreasonable drug treatment group, the difference was statistically significant (both P <0.05). Conclusion In the treatment of gastritis and gastric ulcer patients, irrational use of drugs will cause patients with various adverse reactions, not only affect the patient’s cure rate, but also extend the patient’s treatment time and increase the recurrence rate.