苯经皮肤吸收引起急性中毒尚未见报道。本文报告一例用苯浸泡左脚(患有脚癣)沾的机油后,引起急性苯中毒,一周后呈现以造血系统损害为主的亚急性病程,主要表现为自身免疫性溶血性贫血、粒性白细胞减少、血小板减少症。经治疗后痊愈,随访10年无复发。本例是苯经破损的皮肤引起急性中毒,苯为半抗原,其代谢产物酚可与蛋白质 Benzene poisoned by the skin caused by acute poisoning has not been reported. This article reports a case of benzene soaked left foot (suffering from athlete’s foot) dip oil, causing acute benzene poisoning, a week after the hematopoietic system showed the main sub-acute course of injury, mainly as autoimmune hemolytic anemia, granulocytes Reduce, thrombocytopenia. After treatment healed, no follow-up of 10 years follow-up. This case is caused by benzene damaged skin acute poisoning, benzene is a hapten, the metabolite of phenol and protein