论文部分内容阅读
目的:应用计算机仿真的方法研究Budd-Chiari综合征(BCS)下腔静脉隔膜生长过程中血管的血流动力学变化。方法:基于MRA图像建立下腔静脉隔膜阻塞型BCS血管模型,利用Ansys Fluent软件进行血流参数仿真。结果:成功建立下腔静脉隔膜阻塞型BCS血管模型。模型实验结果显示,在隔膜生长过程中,在下腔静脉及3支主干肝静脉汇合处与隔膜之间有一低速区,该区域面积随隔膜的增长而逐渐变大;随着隔膜的发展,下腔静脉及肝右静脉低剪切力的区域不断扩大,而切应力变大。结论:下腔静脉隔膜的发生发展是一个缓慢变化的过程,可能与下腔静脉壁面剪切力的变化密切相关。
Objective: To study the hemodynamic changes of blood vessels in the inferior vena cava membrane during Budd-Chiari syndrome (BCS) by computer simulation. Methods: The inferior vena cava occlusive BCS vessel model was established based on MRA images and the flow parameters were simulated by Ansys Fluent software. Results: The inferior vena cava occlusive BCS model was successfully established. The model experimental results show that there is a low velocity zone between the confluence of IVC and the three main hepatic veins in the process of diaphragm growth and the area of the zone gradually increases with the increase of diaphragm. With the development of diaphragm, The areas of low shear of the veins and the right hepatic vein continue to expand while the shear stress becomes larger. CONCLUSIONS: The development of inferior vena cava septum is a slow process of change, which may be closely related to the change of wall shear force of inferior vena cava.