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本文以亚铁嗪显色分光光度法检测61例脑血栓形成患者和60例健康对照者血浆抗坏血酸及血浆α-生育酚浓度的结果表明,患者组和对照组的P-AA浓度分别为38.25±17.69和54.83±21.76μmol/L,前者显著低于后者(P<0.001);P—α-TOC浓度分别为19.11±9.35和26.42±8.53μmol/L,前者显著低于后者(P<0.001);提示脑血栓形成患者体内小分子抗氧化剂水平的显著减低可能是脑血栓形成和发展的危险因素之一。
In this paper, the detection of plasma ascorbic acid and plasma α-tocopherol concentration in 61 patients with cerebral thrombosis and 60 healthy controls by ferrous oxazine colorimetric spectrophotometry showed that the concentration of P-AA in patients and controls were 38 and 38 respectively. 25 ± 17.69 and 54.83 ± 21.76μmol / L, respectively, the former was significantly lower than the latter (P <0.001). The concentrations of P-α-TOC were 19.11 ± 9.35 and 26.42 ± 8.53μmol / L, the former was significantly lower than the latter (P <0.001). It is suggested that the significant decrease of small molecule antioxidants in patients with cerebral thrombosis may be one of the risk factors of cerebral thrombosis and development.