吴茱萸碱是吴茱萸果实中的主要生物碱,具有辣椒素样vanilloid受体激动活性,且没有明显的味道,而辣椒素浓烈的辛辣味限制了其在减肥方面的应用。作者用雄性 C3H小鼠和SD大鼠研究了吴茱萸碱和吴茱萸果实提取物预防肥胖的作用。禁食24 h后的小鼠分为2组,1组喂饲普通饲料(对照组),另1组喂饲含0.03％吴茱萸碱的饲料,12天后2组动物禁食1天,尔后处死,立即切除并称量肾周及附睾的脂肪垫。在另一实验中,大鼠分为2组,即高脂 Evodiamine is the main alkaloid in the fruit of E. rutaecarpa. It has capsaicin-like vanilloid receptor agonistic activity and no obvious taste. The strong spicy taste of capsaicin limits its application in weight loss. The authors used male C3H mice and SD rats to study the effects of evodiamine and Wuqi fruit extracts on preventing obesity. After fasting for 24 h, the mice were divided into two groups. The first group was fed with normal feed (control group), the other group was fed with 0.03% evodiamine, and after 12 days, the two groups were fasted for 1 day and then sacrificed. Immediately remove and weigh the fat pads of the kidney and epididymis. In another experiment, rats were divided into 2 groups, namely high fat