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缝隙连接蛋白43可以通过多种方式对心肌细胞的生存调节发挥重要的作用。Cx43的磷酸化水平改变对心肌细胞存活也具有调节作用。Cx43调节心肌细胞的生存对于心脏疾病的发生和发展具有重要的影响,因此很有可能为各类心脏疾病的预防和治疗提供潜在的药物作用新靶点。
Connexin 43 can play an important role in the regulation of cardiomyocytes in many ways. Changes in phosphorylation of Cx43 also have a regulatory effect on cardiomyocyte survival. Cx43 regulates the survival of cardiomyocytes and plays an important role in the occurrence and development of heart disease. Therefore, Cx43 is likely to provide a new target for the potential drug action in the prevention and treatment of various types of heart diseases.