【摘 要】
：
Introduction:The rapidly growing field of regenerative medicine incorporates fundamental principles of stem cell biology and biomedical engineering to repair tissues damaged by genetic disorder,degeneration,or traumatic injury.The global market for stem c
【机 构】
：
Department of Biomedical Engineering,Rutgers,The State University of New Jersey,Piscataway,NJ,USA
论文部分内容阅读
Introduction:The rapidly growing field of regenerative medicine incorporates fundamental principles of stem cell biology and biomedical engineering to repair tissues damaged by genetic disorder,degeneration,or traumatic injury.The global market for stem cell therapies is expanding at an accelerating rate and projected to triple to over 100 Billion USD by the end of the decade(No author listed,2019),as per Figure 1A.
其他文献
Glaucoma is currently the second leading cause of blindness worldwide. Due to aging societies the number of patients suffering from this disease will further increase in the next years. Unfortunately, glaucoma can remain asymptomatic until it is rather fa
Neonatal encephalopathy resulting from an asphyxial episode occurring perinatally is a major cause of death and of permanent neurological disabilities worldwide. Therapeutic hypothermia (TH) started within 6 hours of life and maintained for 72 hours is no
In glaucoma,a leading cause of blindness,retinal ganglion cells are progressively damaged.Intraocular pressure reduction is the only established treatment for glaucoma(Collaborative Normal-Tension Glaucoma Study Group,1998;Vass et al.,2007).
The prevalence of Parkinson\'s disease (PD) is rapidly increasing, and more than 12 million people are expected to suffer from PD by 2040. PD is a highly invalidating neurodegenerative condition that arises from the progressive degeneration of dopaminer
The MATR3 protein was first identified comprising the nuclear matrix, an essential part of preserving the skeletal framework of the nucleus, amongst other nuclear matrins. Composed mainly of intrinsically disordered regions, the protein is made up of 847
The neural retina is a part of the central nervous system. As it lacks regenerative capacity, in an event of injury or disease, neuronal loss leads to visual impairment and often to blindness. Moreover, Müller glia (MG), the predominant glia in the retina
Mammalian central nervous system (CNS) neurons lose axon regenerative ability as they mature. This failure to regenerate shows a clear contrast to a remarkable potential of axon growth during embryonic development and after an injury in the peripheral ner
Formation of the node of Ranvier as a highly coordinated event:Saltatory conduction ensures that information in the vertebrate nervous system is rapidly transmitted over large distances and efficiently processed in complex networks.It requires the insulat
The neuromuscular junction(NMJ)is widely studied for its utility in investigating synaptic properties and processes and neuromuscular changes in response to injury,aging,and disease.
MicroRNA-491-5p (miR-491-5p) plays an important role in regulating cell proliferation and migration; however, the effect of miR-491-5p on neovascularization after traumatic brain injury remains poorly understood. In this study, a controlled cortical injur