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目的：探讨淋巴母细胞性Ｔ细胞淋巴瘤与ＥＢ病毒的关系。方法：收集９例淋巴母细胞性Ｔ细胞淋巴瘤进行ＥＢ病毒检测，用免疫组织化学ＡＢＣ法证实其肿瘤细胞本质；用聚合酶链反应检测ＥＢ病毒特征性ＤＮＡ序列（ＥＢＶＤＮＡ）；用ＲＮＡ原位杂交法检测ＥＢ病毒编码的ＲＮＡ（ＥＢＥＲ１／２）。结果：９例淋巴母细胞性Ｔ细胞淋巴瘤，ＥＢＶＤＮＡ阳性７例（７７．８％），ＥＢＥＲ１／２阳性６例（６６．７％）。结论：淋巴母细胞性Ｔ细胞淋巴瘤与ＥＢ病毒有密切的关系
Objective: To investigate the relationship between lymphoblastic T-cell lymphoma and Epstein-Barr virus. METHODS: Nine cases of lymphoblastic T-cell lymphoma were collected for Epstein-Barr virus detection. The nature of tumor cells was confirmed by immunohistochemical ABC method. Epstein-Barr virus-characterized DNA sequence (EBVDNA) was detected by polymerase chain reaction; RNA was used in situ. The EB virus-encoded RNA (EBER1/2) was detected by hybridization. Results: In 9 cases of lymphoblastic T-cell lymphoma, 7 cases (77.8%) were positive for EBV DNA and 6 cases (66.7%) were EBER1/2 positive. Conclusion: Lymphoblastoid T-cell lymphoma is closely related to Epstein-Barr virus