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人工流产术是针对避孕失败的常规补救措施之一,是妇科门诊的常见手术。初孕妇女宫颈口较紧,人工流产术中发生宫颈裂伤、子宫穿孔等综合反应风险较高,对手术效果及安全性造成了极大影响[1]。米索前列醇可加速宫颈胶原裂解,已广泛应用于人工流产术。近年来,一种新型抗孕激素米非司酮在人工流产术中的应用受到了广泛关注[2]。米非司酮具有甾体结构,可与内源性孕酮竞争结合受体,产生较强的抗孕酮作用[3]。为分析米非司酮联合米索前列醇
Induced abortion is one of the common remedies for the failure of contraception and is a common operation in gynecology clinics. First trimester of women’s cervix tight, abortion occurred in cervical laceration, uterine perforation and other comprehensive response to a higher risk of surgical effects and safety caused a great impact [1]. Misoprostol can accelerate cervical collagen lysis, has been widely used in artificial abortion. In recent years, a new type of anti-progestin mifepristone in the application of artificial abortion has received widespread attention [2]. Mifepristone has a steroidal structure that competes with the endogenous progesterone for binding to the receptor and produces a stronger antiprogestin effect [3]. To analyze mifepristone in combination with misoprostol