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目的分析非小细胞肺癌的临床特点和预后影响因素。方法对43例非小细胞肺癌患者的临床资料进行回顾性分析。结果首次就诊致使误诊15例,首次误诊率高达34.88%。有肿瘤家族史者4例,肺癌家族史者1例。有职业接触史者1例,无职业接触史者42例。肿瘤TNM分期:ⅠA期2例、ⅠB期5例、ⅡA期1例、ⅡB期3例、ⅢA期4例、ⅢB期12例、Ⅳ期16例。临床表现主要为咳嗽、胸闷、咳痰、气促、咳血、发热、消瘦等。病理类型:腺癌19例,鳞癌20例,腺鳞癌2例,其他2例。单因素分析表明,性别、年龄、吸烟与否、组织学分化程度、手术类型等因素与非小细胞肺癌患者的长期生存相关。结论非小细胞肺癌呈现一定的临床特点,组织学分化程度高、合理治疗者生存期长。
Objective To analyze the clinical features and prognostic factors of non-small cell lung cancer. Methods The clinical data of 43 patients with non-small cell lung cancer were analyzed retrospectively. Results The first visit led to misdiagnosis in 15 cases, the first misdiagnosis rate as high as 34.88%. Family history of tumor in 4 cases, 1 case of family history of lung cancer. A history of occupational exposure in 1 case, no history of occupational exposure in 42 cases. TNM staging of tumor: 2 cases of stage IA, 5 cases of stage IB, 1 case of stage IIA, 3 cases of stage IIB, 4 cases of stage IIIA, 12 cases of stage IIIB and 16 cases of stage IV. The main clinical manifestations of cough, chest tightness, expectoration, shortness of breath, hemoptysis, fever, weight loss and so on. Pathological types: adenocarcinoma in 19 cases, squamous cell carcinoma in 20 cases, adenosquamous carcinoma in 2 cases, the other 2 cases. Univariate analysis showed that gender, age, smoking or not, histological differentiation, type of surgery and other factors associated with the long-term survival of patients with non-small cell lung cancer. Conclusion Non-small cell lung cancer has some clinical features, histological differentiation is high, reasonable treatment of long survival.