脑胶质瘤为神经外科的常见病、多发病 ,约占颅内肿瘤的 45 % ,其主要治疗手段包括手术切除、化学治疗与放射治疗 ,其生存时间短、预后差 ,平均生存时间不足 1年 ,这与其具有高增殖性及高侵袭性有关。本实验应用腺病毒作为载体介导抑癌基因PTEN体外转染人脑胶质瘤细胞U87,检测其 Glioma is a common disease of neurosurgery, frequently-occurring disease, accounting for 45% of intracranial tumors, the main treatment methods include surgical resection, chemotherapy and radiation therapy, its survival time is short, the prognosis is poor, the average survival time less than 1 Year, which is related to its high proliferation and aggressiveness. In this study, adenovirus vector-mediated tumor suppressor gene PTEN transfected human glioma U87 cells in vitro