论文部分内容阅读
目的评价比索洛尔对心力衰竭合并持续性房颤的疗效。方法选取心力衰竭合并持续性房颤患者76例，随机分为观察组与对照组各38例，两组均给予原发病内科的常规治疗。观察组在常规治疗基础上采用比索洛尔片0.25~10mg，1次/d；对照组在常规治疗基础上口服胺碘酮片至少200mg,1次/d，维持4w。结果两组患者治疗后的心功能明显改善，与治疗前比较，均有统计学意义(<0.05)；治疗后两组心室率控制比较，观察组明显优于对照组(<0.05)；观察药物不良反应，胺碘酮组高于比索洛尔组。结论比索洛尔治疗心衰合并持续性房颤具有良好的疗效，副反应少，是控制心衰合并房颤常规的优化的一线用药。“,”Objective To evaluate the therapeutic ef ect of Bisoprolol on heart failure patients with persistent atrial fibril ation . Methods 76 heart failure patients with persistent atrial fibril ation were randomly divided into observation group and control group with 38 cases in each group, two groups were given conventional treatment of the primary disease in Department of internal medicine. The observation group in the conventional treatment were treated on the basis of using bisoprolol tablets from 0.25 to 10mg, 1 times/day, lasting for 4 weeks;the control group was treated on the basis of oral Amiodarone pieces of at least 200mg, 1 times/ day, for 4 weeks. Results The cardiac function of two groups after treatment significantly improved, compared with that before treatment, there were statistical significance ( <0.05);comparison of the two groups after treatment in control ing ventricular rate , the observation group was significantly bet er than the cont group( <0.05); observation of adverse reactions to drugs, Amiodarone group was higher than that of Bisoprolol group. Conclusion Bisoprolol in treatment of congestive heart failure with persistent atrial fibril ation has good curative ef ect, less side reaction, is a first-line refined conventional drug to optimizing control of heart failure complicated with atrial fibril ation.