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[目的]探讨山西省女性生殖系肿瘤的影响因素,以及良、恶性女性生殖系肿瘤相关因素的差别。[方法]选择2006年1月～12月在山西医科大学第二医院和儿童医院妇科住院的711例确诊为妇科生殖系统原发肿瘤的患者和同期确诊的154例住院的妇科炎症患者为研究对象,按照现行诊断标准分为恶、良性肿瘤组和对照组,对其相关因素进行统计分析。[结果]妇科恶性肿瘤组、良性肿瘤组与对照组的单因素比较:平均年龄、平均结婚年龄、平均初潮年龄、平均妊娠次数、平均生产次数、平均流产次数、绝经在三组中的分布差异有统计学意义(P<0.05);吸烟者、饮酒者在三组的分布无统计学差异(P>0.05)。妇科恶性肿瘤组与对照组的多元Logist回归分析,年龄、结婚年龄、绝经、孕次、产次、流产次数作为主要效应因素引入回归模型;良性肿瘤组与对照组的多元Logistic回归分析,年龄、绝经和流产次数作为主效应因素引入回归模型;而恶性组与良性组比较,绝经、结婚年龄和产次作为主效应因素引入回归模型。[结论]绝经、多孕次是恶性肿瘤的保护因素;年龄大、早婚、多产、多次流产是危险因素。良性肿瘤的保护因素为绝经,而危险因素为年龄大和多次流产。
[Objective] To explore the influencing factors of female reproductive system tumors in Shanxi Province and the differences of related factors between female and male genital tumors. [Methods] From January 2006 to December 2006, 711 patients with gynecologic inflammation diagnosed as gynecologic reproductive system in gynecology hospital of the Second Hospital of Shanxi Medical University and Children’s Hospital and 154 hospitalized patients with gynecological inflammation were enrolled in this study. , According to the current diagnostic criteria is divided into evil, benign tumor group and control group, and its related factors for statistical analysis. [Results] The single factor comparison between the gynecological malignant tumor group, the benign tumor group and the control group: the average age, the average marriage age, the average menarche age, the average number of pregnancy, the average number of times of miscarriage, the distribution of menopause in three groups (P <0.05). There was no significant difference in the distribution of smokers and drinkers between the three groups (P> 0.05). Multivariate logistic regression analysis, age, marriage age, menopause, gestational age, parity and miscarriage frequency were used as the main effect factors in the gynecological malignant tumor group and the control group, respectively. Logistic regression analysis, multivariate Logistic regression analysis, Menopause and abortion as the main effect factors into the regression model; and malignant group compared with benign group, menopause, marriage age and parity as the main effect factor into the regression model. [Conclusion] Menopausal and multiple pregnancies are the protective factors of malignant tumors. The older, the older married, the more productive and the multiple miscarriage are the risk factors. The protective factor for benign tumors is menopause, while the risk factors are older and multiple abortions.