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目的 评价盆腔脏器联合切除术 (PE)对局部进展期直肠癌的疗效。方法 对 12年中 79例局部进展期直肠癌PE术后结果进行回顾性总结。结果 全盆腔脏器切除术 (TPE) 4 6例 ,其中保肛TPE 5例 ,TPE联合骶骨切除 1例 ,TPE联合半骨盆切除 1例 ,后盆腔脏器切除术 (PPE) 33例。根治性切除 6 5例 (82 8% ) ,合并症发生率 4 8 6 % ,手术死亡 2例 (2 5 % ) ,根治术后再复发 36例 (5 8 1% ) ,术后 1、3、5年生存率 75 8%、39 3%、35 8%。根治性切除与大体根治切除术后 3年、5年生存率分别为 4 4 2 %、4 0 8%与 11 1%、0。结论 PE是目前治疗局部进展期直肠癌有效的方法 ,积极的根治性切除病灶 ,可以有效提高其治愈率 ,改善生活质量
Objective To evaluate the curative effect of pelvic organ excision (PE) on locally advanced rectal cancer. Methods A retrospective review was made on the results of 79 patients with locally advanced rectal cancer after 12 years. Results Forty - six cases underwent total pelvic organ resection (TPE), including 5 cases of TPE, 1 case of TPE combined with sacral resection, 1 case of TPE combined with semi - pelvic resection and 33 cases of pelvic organ resection (PPE). There were 65 cases (82.8%) with radical resection, 486% with complications, 2 cases with operative death (25%), 36 cases (581%) with recurrence after radical operation, , 5-year survival rates 75 8%, 39 3%, 35 8%. Three years after radical resection and radical resection, the 5-year survival rates were 44.2%, 40.8% and 11.1%, respectively. Conclusion PE is an effective method for the treatment of locally advanced rectal cancer, and aggressive radical resection of the lesion can effectively improve the cure rate and improve the quality of life