以甲酰胺和氯丙酮等为原料合成了离子液体4-甲基-3-丁基噻唑硫酸氢盐。以aldol反应为探针,探究了离子液体催化苯甲醛与丙酮的缩合反应,并对催化剂用量、醛酮比、反应时间和催化剂重复利用等进行了考察。优化工艺条件为:n(苯甲醛)∶n(丙酮)=1.0∶1.8,催化剂用量3%(n/n),反应时间1.5 h,苄叉丙酮的收率达81.2%,催化剂重复使用5次仍可保持较高催化效果。 Ionic liquid 4-methyl-3-butylthiazole hydrogensulfate was synthesized from formamide and chloroacetone. The aldol reaction was used as a probe to investigate the condensation reaction of benzaldehyde and acetone catalyzed by ionic liquid. The effects of the amount of catalyst, the ratio of aldehyde to ketone, the reaction time and the catalyst recycle were investigated. The optimal reaction conditions were n (benzaldehyde): n (acetone) = 1.0:1.8, catalyst amount 3% (n / n), reaction time 1.5 h, the yield of benzylidene acetone was 81.2% and the catalyst was reused 5 times Still maintain a high catalytic effect.