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目的探讨生长抑素8肽(善宁)治疗溃疡性上消化道出血的疗效。方法选择58例急性溃疡性上消化道中、大量出血患者,随机分成二组。对照组31例用西咪替丁治疗,观察组27例用善宁治疗,观察用药后24h、48h止血情况。结果对照组止血有效率为67.74%,观察组止血率为92.59%,观察组止血有效率明显优于对照组,二者比较差异有统计学意义(P<0.05),观察过程未见不良反应。结论善宁治疗溃疡性上消化道出血的疗效显著,安全可靠,值得推广应用。
Objective To investigate the efficacy of somatostatin 8 peptide (Shanning) in the treatment of ulcer upper gastrointestinal bleeding. Methods A total of 58 cases of acute ulcer in the upper digestive tract, a large number of bleeding patients were randomly divided into two groups. In the control group, 31 cases were treated with cimetidine. In the observation group, 27 cases were treated with Shanning, and the hemostasis was observed 24h and 48h after treatment. Results The effective rate of hemostasis in the control group was 67.74%, and the rate of hemostasis in the observation group was 92.59%. The effective rate of hemostasis in the observation group was significantly better than that in the control group. The difference was statistically significant (P <0.05). No adverse reactions were observed during the observation. Conclusion Shannon treatment of ulcerative upper gastrointestinal bleeding significant effect, safe and reliable, it is worth promoting the application.